West Ham make three changes for the derby at the London Stadium, with Sam Byram, Aaron Cresswell and Mark Noble coming in.
The Hammers are without Andy Carroll and Arthur Masuaku, who are sidelined with groin and foot problems respectively.
Meanwhile, Kyle Walker returns to the Tottenham starting line-up.
West Ham: Adrian, Fonte, Reid, Collins, Byram, Kouyate, Noble, Cresswell, Lanzini, Ayew, Calleri.
Subs: Randolph, Nordtveit, Feghouli, Snodgrass, Fletcher, Fernandes, Rice.
Tottenham: Lloris, Walker, Alderweireld, Vertonghen, Davies, Dier, Wanyama, Son, Eriksen, Alli, Kane.
Subs: Vorm, Trippier, Wimmer, Dembele, Nkoudou, Sissoko, Janssen.