Tottenham boss Antonio Conte has made two changes to the side from the draw against Southampton.
Lucas Moura and Oliver Skipp are recalled, with Harry Winks and Dele Alli on the bench.
Midfielder Giovani Lo Celso is also on the bench after a calf problem.
Watford make three changes, with William Troost-Ekong, Imran Louza and Ken Sema coming in.
Watford: Bachmann, Ekong, Cathcart, Masina, Sierralta, Sissoko, Sema, Kucka, Louza, King, Dennis.
Subs: Angelini, Ngakia, Cleverley, Joao Pedro, Gosling, Fletcher, Tufan, Hernandez, Morris.
Tottenham: Lloris, Sanchez, Dier, Davies, Reguilon, Royal, Skipp, Hojbjerg, Moura, Son, Kane.
Subs: Gollini, Doherty, Winks, Gil, Rodon, Lo Celso, Alli, Tanganga, Ndombele.