Antonio Rudiger and youngster Jeremie Boga make their Premier League debuts for Chelsea.
With Pedro out injured and Victor Moses suspended, summer signing Rudiger has been brought in along with the 20-year-old Boga.
Michy Batshuayi leads the champions’ attack, with record signing Alvaro Morata on the bench.
For Burnley, former Chelsea man Jack Cork makes his debut following his recent move to the Lancashire club.
Chelsea: Courtois; Rudiger, Luiz, Cahill; Azpilicueta, Kante, Fabregas, Alonso; Willian, Batshuayi, Boga.
Subs: Caballero, Christensen, Tomori, Scott, Musonda, Kenedy, Morata.
Burnley: Heaton; Lowton, Tarkowski, Mee, Ward; Gudmundsson, Cork, Hendrick, Defour, Brady; Vokes.
Subs: Pope, Taylor, Westwood, Long, Arfield, Walters, Barnes.