Fit-again trio Hector Bellerin, Kieran Gibbs and Francis Coquelin are all on the bench for Arsenal for the game at the Emirates Stadium.
Olivier Giroud starts for the Gunners after shaking off an ankle problem, but Theo Walcott is out with a calf injury.
For Burnley, Dean Marney and Ashley Barnes return after injury but winger Scott Arfield is still out with with a hamstring problem.
Arsenal: Cech, Gabriel, Mustafi, Koscielny, Monreal, Ramsey, Xhaka, Alexis, Ozil, Iwobi, Giroud.
Subs: Ospina, Gibbs, Bellerin, Coquelin, Oxlade-Chamberlain, Welbeck, Lucas.
Burnley: Heaton, Lowton, Keane, Mee, Ward, Boyd, Marney, Hendrick, Defour, Barnes, Gray.
Subs: Flanaghan, Kightly, Barton, Vokes, Robinson, Darikwa, Tarkowski.