Olivier Giroud makes only his third start of the season as Arsenal make four changes to their line-up against Paris St-Germain.
The French striker, who came off the bench to score the equaliser at Manchester United on Saturday, heads an attack-minded line-up, with the already-qualified Gunners looking to top their Champions League group with a game to spare.
Alexis Sanchez, Mesut Ozil and Alex Iwobi line up behind Giroud, with Aaron Ramsey sitting in alongside Francis Coquelin.
David Ospina replaced Petr Cech in goal, with Kieran Gibbs returning at left-back.
Nacho Monreal, Mohamed Elneny and Theo Walcott drop to the bench.
PSG are without Ivory Coast right-back Serge Aurier, who has been denied a visa to enter the UK following a conviction in September for assaulting a police officer.
Arsenal drew 1-1 in Paris on the first matchday, despite falling behind to Edinson Cavani’s goal after 42 seconds.
Arsenal: Ospina; Jenkinson, Mustafi, Koscielny, Gibbs; Coquelin, Ramsey; Sanchez, Ozil, Iwobi; Giroud.
Subs: Cech, Gabriel, Monreal, Xhaka, Elneny, Oxlade-Chamberlain, Walcott.
PSG: Areola; Meunier, Marquinhos, Thiago Silva, Maxwell; Verratti, Krychowiak, Thiago Motta; Lucas, Cavani, Matuidi.
Subs: Trapp, Kimpembe, Ben Arfa, Jese, Nkunku, Augustin, Ikone.