Tottenham’s £23m signing Lucas Moura has been named in the squad for the north London derby with Arsenal, who are without last weekend’s hat-trick hero Aaron Ramsey.
Spurs boss Mauricio Pochettino has named the same team that started against Liverpool in their last Premier League match.
It means he sticks with Davinson Sanchez and Jan Vertonghen in a back four, rather than giving the fit-again Toby Alderweireld his first league start since October.
Danny Rose, who also returned from injuries to play in the midweek FA Cup win over Newport County, is on the bench alongside Moura.
Ramsey is the biggest absentee from the Arsenal line-up, with goalkeeper Petr Cech passed fit despite being substituted with a calf injury during the win over Everton last week.
Mohamed Elneny comes in for Ramsey while Jack Wilshere relegates Alex Iwobi to the bench.
This is the first game between the sides at Wembley since April 1993, when a goal by Tony Adams gave Arsenal a 1-0 FA Cup semi-final victory.
Tottenham: Lloris; Trippier, Sanchez, Vertonghen, Davies; Dier, Dembele; Eriksen, Alli, Son; Kane.
Subs: Vorm, Aurier, Rose, Wanyama, Sissoko, Lamela, Moura.
Arsenal: Cech; Bellerin, Mustafi, Koscielny, Monreal; Elneny, Xhaka; Wilshere, Ozil, Mkhitaryan; Aubameyang.
Subs: Ospina, Chambers, Kolasinac, Maitland-Niles, Iwobi, Welbeck, Lacazette.