Tottenham will assess Dele Alli for the trip to Brighton after he returned to training following a hamstring injury.
Moussa Sissoko (knee) is also back in training but Hugo Lloris (thigh) will again miss out.
Toby Alderweireld and Kieran Trippier will be back in the squad after they were rested at Inter Milan.
Provisional squad: Vorm, Gazzaniga, Trippier, Walker-Peters, Alderweireld, Vertonghen, Rose, Sanchez, Davies, Dier, Wanyama, Dembele, Eriksen, Lamela, Winks, Moura, Son, Llorente, Kane.
Pascal Gross remains Brighton’s only absentee ahead.
The German midfielder, who missed Monday’s draw at Southampton, is sidelined with an ankle injury sustained against Fulham before the international break.
Winger Jose Izquierdo and forward Florin Andone are awaiting their first appearances of the season after returning to fitness.
Provisional squad: Ryan, Button, Steele, Bernardo, Montoya, Bruno, Bong, Dunk, Duffy, Balogun, Schelotto, Suttner, Bissouma, Stephens, Propper, Kayal, Knockaert, March, Jahanbakhsh, Izquierdo, Andone, Locadia, Murray.