West Ham are without the suspended Andy Carroll and the injured Diafra Sakho, but Javier Hernandez has been passed fit after recovering from a slight hamstring problem.
The Hammers make two changes, with Arthur Masuaki and Pedro Obiang coming into the starting line-up.
For Brighton, Shane Duffy, who went off against Everton with a groin problem, has been passed fit to play. Tomer Hemed is suspended.
West Ham: Hart, Zabaleta, Reid, Fonte, Masuaku, Obiang, Kouyate, Lanzini, Antonio, Arnautovic, Hernandez.
Subs: Adrian, Ogbonna, Cresswell, Noble, Fernandes, Ayew.
Brighton: Ryan, Bruno, Dunk, Duffy, Bong, Knockaert, Stephens, Propper, Izquierdo, Gross, Murray.
Subs: Krul, Goldson, March, Schelotto, Suttner, Brown, Molumby.