Chelsea wing-back Marcos Alonso serves the second game of his three-match ban for violent conduct.
Emerson played in the Spaniard’s place at Burnley and will be assessed to see if he is fit enough to play again in this weekend’s FA Cup semi-final.
Danny Drinkwater remains a doubt for the game at Wembley because of a groin problem. David Luiz and Ethan Ampadu are sidelined due to respective knee and ankle injuries.
Provisional squad: Courtois, Caballero, Eduardo, Azpilicueta, Cahill, Christensen, Rudiger, Emerson, Zappacosta, Moses, Kante, Drinkwater, Fabregas, Bakayoko, Barkley, Willian, Hazard, Pedro, Giroud, Morata.
Southampton will monitor Mario Lemina and Sofiane Boufa.
Midfielder Lemina has been suffering with back and hamstring problems, while winger Boufal is ill and both men missed Thursday’s 0-0 draw at Leicester.
Saints centre-back Jack Stephens completes his three-match ban, with manager Mark Hughes suggesting he could make changes.
Provisional squad: Forster, McCarthy, Taylor, McQueen, Soares, Pied, Bertrand, Bednarek, Hoedt, Lemina, Yoshida, Davis, Romeu, Boufal, Ward-Prowse, Hojbjerg, Long, Redmond, Tadic, Sims, Gabbiadini, Austin, Carrillo.
Top goalscorers (all competitions): Eden Hazard (Chelsea) 16; Charlie Austin (Southampton) 7
Match odds: Chelsea 1-2, Draw 16-5, Southampton 11-2
Referee: Martin Atkinson (West Yorkshire)