Arsenal boss Mikel Arteta makes four changes from the 3-3 draw against West Ham.
David Luiz has a knee injury and Pablo Mari is dropped to the bench at the Emirates Stadium, where Gabriel partners Rob Holding in central defence.
In midfield, Dani Ceballos and Nicolas Pepe come in for Granit Xhaka, who is ill, and Bukayo Saka, who has a hamstring problem.
Liverpool, meanwhile, make two changes. Roberto Firmino returns after a knee injury and there is also a recall to the Reds’ starting line-up for James Milner.
Arsenal: Leno, Chambers, Holding, Gabriel, Tierney, Partey, Ceballos, Aubameyang, Odegaard, Pepe, Lacazette.
Subs: Ryan, Bellerin, Willian, Soares, Mari, Nelson, Elneny, Nketiah, Martinelli.
Liverpool: Alisson, Alexander-Arnold, Phillips, Kabak, Robertson, Fabinho, Milner, Thiago, Mane, Firminho, Salah.
Subs: Adrian, Wijnaldum, Kieta, Oxlade-Chamberlain, Jones, Jota, Tsimikas, Shaqiri, Williams.