Arsenal make two changes, with Mesut Ozil returning to the starting line-up as captain after being passed fit following a back problem and Stephan Lichtsteiner also coming in.
Lichtsteiner makes his full Premier League debut and replaces Nacho Monreal, while Ozil’s inclusion means Danny Welbeck drops to the bench.
Leicester, meanwhile, are without captain Wes Morgan, who serves a one-match ban after being sent off against Everton.
Morgan is replaced by Jonny Evans – the Foxes’ only change.
Arsenal: Leno, Bellerin, Mustafi, Holding, Lichtsteiner, Mkhitaryan, Torreira, Xhaka, Ozil, Iwobi, Lacazette.
Subs: Martinez, Ramsey, Aubameyang, Welbeck, Guendouzi, Medley, Smith-Rowe.
Leicester: Schmeichel, Amartey, Evans, Maguire, Chilwell, Pereira, Mendy, Ndidi, Maddison, Iheanacho, Vardy.
Subs: Ward, Soyuncu, Albrighton, Okazaki, Iborra, Fuchs, Ghezzal.